Genestra Methylation Support 90 Capsules
Supports healthy homocysteine levels* • Helps to promote vitamin B12 intake* • Provides 1500 mg of betaine and 75 mg of choline per day • Includes 50 mg of vitamin B6, 800 mcg of vitamin B12 and 400 mcg of folate (from Metafolin®) per day
Methylation Support provides a combination of betaine, choline, and B vitamins in their physiologically active form to help support homocysteine metabolism.1,2 Homocysteine is an amino acid that can be further metabolized into methionine or cysteine, and normal homocysteine levels are necessary for the methylation of nucleic acids, proteins and lipids, as well as protein production.1 A randomized, double-blind trial involving 76 adults demonstrated that supplementation with 1.5 g of betaine daily for six weeks significantly better maintained homocysteine levels when compared to a placebo treatment.3 As a result of their interrelated pathways, it is important to have metabolic balances between choline, betaine, homocysteine, vitamin B6, vitamin B12 and folate.4 Methylation Support is ideal for vegans, who tend to consume low levels of vitamin B12.2
REFERENCES 1. Selhub, J. Public health significance of elevated homocysteine. Food and Nutrition Bulletin. 2008; 29(2 Suppl): S116-S125. 2. Combs, GF. (2012). The Vitamins (4th ed.). USA: Elsevier. 3. Olthof, MR, van Vliet, T, Boelsma, E, Verhoef, P. Low Dose Betaine Supplementation Leads to Immediate and Long Term Lowering of Plasma Homocysteine in Healthy Men and Women. J. Nutr. 2003; 133: 02372-page-001.jpg4135–4138. 4. Michel, V, Yuan, Z, Ramsubir, S, Bakovic, M. Choline Transport for Phospholipid Synthesis. Exp Biol Med. 2006; 231: 490–504.
Key Ingredients: Choline, Folate, Vitamin B12, Vitamin B6